Syn-BNP (3.85)

General Information


DRACP ID  DRACP01916

Peptide Name   Syn-BNP (3.85)

Sequence  sRxRtLxTTnGT

Sequence Length  12

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
HT-29 Colon adenocarcinoma Carcinoma LC>128 µg/ml MTT assay 20 h 1

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  C14OH

C-terminal Modification  Free

Other Modification  s=D-Ser; x=D-Dab; t=D=Thr; n=D-Asn

Chiral  Mix



Physicochemical Information


Formula  C32H51N13O6

Absent amino acids  ACDEFHIKMNPQSVWY

Common amino acids  T

Mass  91021

Pl  12.5

Basic residues  2

Acidic residues  0

Hydrophobic residues  1

Net charge  2

Boman Index  -3169

Hydrophobicity  -64.17

Aliphatic Index  32.5

Half Life 
  /

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  4

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 28055186

Title  Antimicrobials Inspired by Nonribosomal Peptide Synthetase Gene Clusters

Doi 10.1021/jacs.6b11861

Year  2017

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  DBAASPS_11205

DRACP is developed by Dr.Zheng's team.