This work is licensed under a Creative Commons Attribution 4.0 International License.
CRAMP (20-35)
General Information
DRACP ID DRACP01921
Peptide Name CRAMP (20-35)
Sequence KKIGQKIKNFFQKL
Sequence Length 14
UniProt ID P51437
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| Hep-G2 | Hepatoblastoma | Blastoma | EC50>50µM | MTT assay | 24 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C82H138N22O18
Absent amino acids ACDEHMPRSTVWY
Common amino acids K
Mass 195220
Pl 11.4
Basic residues 5
Acidic residues 0
Hydrophobic residues 5
Net charge 5
Boman Index -2381
Hydrophobicity -85.71
Aliphatic Index 83.57
Half Life
Mammalian: 100 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30176261
Title Structure-activity relationship study of the antimicrobial CRAMP-derived peptide CRAMP20-33
Doi 10.1016/j.peptides.2018.08.013
Year 2018
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPS_12498
This work is licensed under a Creative Commons Attribution 4.0 International License.