This work is licensed under a Creative Commons Attribution 4.0 International License.
FGR (7-22)-X13, FGF-X13
General Information
DRACP ID DRACP01936
Peptide Name FGR (7-22)-X13, FGF-X13
Sequence AAVALLPAVLLALLAPMPFSTGKRIMLGE
Sequence Length 29
UniProt ID P08620
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| OCI-AML3 | Adult acute myeloid leukemia; Acute myeloid leukemia | Leukemia | Not active up to 100 µM | CellTox cytotoxicity assay | 30 min | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity HEK293: Not active up to 100 µM; HFF: Not active up to 100 µM
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C138H235N33O34S2
Absent amino acids CDHNQWY
Common amino acids L
Mass 346435
Pl 9.69
Basic residues 2
Acidic residues 1
Hydrophobic residues 17
Net charge 1
Boman Index 3461
Hydrophobicity 130.69
Aliphatic Index 148.28
Half Life
Mammalian: 0.8 hour
Yeast: 10 min
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 4
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 26734838
Title Use of a novel cytotoxic HEXIM1 peptide in the directed breast cancer therapy
Year 2016
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPS_12678
This work is licensed under a Creative Commons Attribution 4.0 International License.