This work is licensed under a Creative Commons Attribution 4.0 International License.
1
General Information
DRACP ID DRACP01945
Peptide Name 1
Sequence ALFGILKKAFGKILTIFAGLPGVV
Sequence Length 24
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP Membrane-targeted
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| A549 | Lung adenocarcinoma | Carcinoma | EC50=8.6 μM | MTT assay | 24 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C123H201N27O26
Absent amino acids CDEHMNQRSWY
Common amino acids GL
Mass 288457
Pl 11.1
Basic residues 3
Acidic residues 0
Hydrophobic residues 15
Net charge 3
Boman Index 4143
Hydrophobicity 147.08
Aliphatic Index 150.42
Half Life
Mammalian: 4.4 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 5
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30953170
Title De novo design of anticancer peptides by ensemble artificial neural networks
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPS_13109
This work is licensed under a Creative Commons Attribution 4.0 International License.