This work is licensed under a Creative Commons Attribution 4.0 International License.
6
General Information
DRACP ID DRACP01950
Peptide Name 6
Sequence FLGPTIGKIAKFILKHIVGLGDAALV
Sequence Length 26
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP Membrane-targeted
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| A549 | Lung adenocarcinoma | Carcinoma | EC50=10.7 μM | MTT assay | 24 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C130H215N31O30
Absent amino acids CEMNQRSWY
Common amino acids GIL
Mass 313847
Pl 10.51
Basic residues 4
Acidic residues 1
Hydrophobic residues 15
Net charge 3
Boman Index 2999
Hydrophobicity 116.54
Aliphatic Index 153.85
Half Life
Mammalian: 20 hour
Yeast: 30 min
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 5
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30953170
Title De novo design of anticancer peptides by ensemble artificial neural networks
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPS_13114
This work is licensed under a Creative Commons Attribution 4.0 International License.