This work is licensed under a Creative Commons Attribution 4.0 International License.
7
General Information
DRACP ID DRACP01951
Peptide Name 7
Sequence GIVTILKGAVGVILGGL
Sequence Length 17
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP Membrane-targeted
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| A549 | Lung adenocarcinoma | Carcinoma | EC50>100 μM | MTT assay | 24 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C74H134N18O19
Absent amino acids CDEFHMNPQRSWY
Common amino acids G
Mass 186559
Pl 9.7
Basic residues 1
Acidic residues 0
Hydrophobic residues 10
Net charge 1
Boman Index 4003
Hydrophobicity 192.35
Aliphatic Index 194.71
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 6
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30953170
Title De novo design of anticancer peptides by ensemble artificial neural networks
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPS_13116
This work is licensed under a Creative Commons Attribution 4.0 International License.