This work is licensed under a Creative Commons Attribution 4.0 International License.
14
General Information
DRACP ID DRACP01958
Peptide Name 14
Sequence GLWGVIKALGGHVG
Sequence Length 14
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP Membrane-targeted
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| A549 | Lung adenocarcinoma | Carcinoma | EC50>100 μM | MTT assay | 24 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C64H102N18O15
Absent amino acids CDEFMNPQRSTY
Common amino acids G
Mass 159571
Pl 9.7
Basic residues 2
Acidic residues 0
Hydrophobic residues 7
Net charge 2
Boman Index 2147
Hydrophobicity 87.86
Aliphatic Index 132.14
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 5500
Absorbance 280nm 423.08
Polar residues 5
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30953170
Title De novo design of anticancer peptides by ensemble artificial neural networks
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPS_13160
This work is licensed under a Creative Commons Attribution 4.0 International License.