This work is licensed under a Creative Commons Attribution 4.0 International License.
KA081020-065
General Information
DRACP ID DRACP02003
Peptide Name KA081020-065
Sequence MRGENMSEGNRPEGTPHGLRSTPARELPIPAFLEPAR
Sequence Length 37
UniProt ID I3TKW5
PubChem CID Not available
Origin Tistrella mobilis (strain KA081020-065)
Type Native peptide
Classification
Not available
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HeLa | Human papillomavirus-related endocervical adenocarcinoma | Carcinoma | Not available | Not available | Not available | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C173H280N56O54S2
Absent amino acids CDKQVWY
Common amino acids P
Mass 471486
Pl 7.56
Basic residues 6
Acidic residues 5
Hydrophobic residues 8
Net charge 1
Boman Index -10198
Hydrophobicity -98.65
Aliphatic Index 50.27
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 10
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 22458477
Title Bacterial biosynthesis and maturation of the didemnin anti-cancer agents
Year 2012
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.