This work is licensed under a Creative Commons Attribution 4.0 International License.
EP3
General Information
DRACP ID DRACP02038
Peptide Name EP3
Sequence AMVGT
Sequence Length 5
UniProt ID Not available
PubChem CID Not available
Origin Eisenia fetida
Type Native peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| MGC-803 | Gastric mucinous adenocarcinoma | Carcinoma | Observed by scanning electronic microscopy | MTT assay | 24 h, 48 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Short peptides with 5–7 amino acid residuals formed multimers in the PB buffer, which was a more likely explanation for the mechanism of EP3.
Nature Anticancer; Antimicrobial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Acetylation
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C19H35N5O7S
Absent amino acids CDEFHIKLNPQRSWY
Common amino acids AGMTV
Mass 54911
Pl 6.11
Basic residues 0
Acidic residues 0
Hydrophobic residues 2
Net charge 0
Boman Index 657
Hydrophobicity 136
Aliphatic Index 78
Half Life
Mammalian: 4.4 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title A novel antimicrobial vermipeptide family from earthworm Eisenia fetida
Doi 10.1016/j.ejsobi.2007.08.048
Year 2007
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPR_4319
This work is licensed under a Creative Commons Attribution 4.0 International License.