VitE-KAaK

General Information


DRACP ID  DRACP02047

Peptide Name   VitE-KAaK

Sequence  KAaK

Sequence Length  4

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
RAW 264.7 Mouse macrophage leukemia cell Leukemia LC50 >100 µM XTT assay 16 h 1

Hemolytic Activity  Human erythrocytes: 50% Hemolysis=120 µM

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antimicrobial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Vitamin E succinate

C-terminal Modification  Amidation

Other Modification  k=D-Lys

Chiral  Mix



Physicochemical Information


Formula  C15H29N5O3

Absent amino acids  CDEFGHILMNPQRSTVWY

Common amino acids  K

Mass  38112

Pl  10.81

Basic residues  2

Acidic residues  0

Hydrophobic residues  1

Net charge  2

Boman Index  -929

Hydrophobicity  -150

Aliphatic Index  25

Half Life 
  /

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 22006001

Title  Ultrashort peptide bioconjugates are exclusively antifungal agents and synergize with cyclodextrin and amphotericin B

Doi 10.1128/AAC.00468-11

Year  2012

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.