This work is licensed under a Creative Commons Attribution 4.0 International License.
VitE-KKK
General Information
DRACP ID DRACP02048
Peptide Name VitE-KKK
Sequence KKK
Sequence Length 3
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| RAW 264.7 | Mouse macrophage leukemia cell | Leukemia | LC50 =70 µM | XTT assay | 16 h | 1 |
Hemolytic Activity Human erythrocytes: 50% Hemolysis=60 µM
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antimicrobial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Vitamin E succinate
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C18H38N6O4
Absent amino acids ACDEFGHILMNPQRSTVWY
Common amino acids K
Mass 43839
Pl 11.1
Basic residues 3
Acidic residues 0
Hydrophobic residues 0
Net charge 3
Boman Index -1665
Hydrophobicity -390
Aliphatic Index 0
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 22006001
Title Ultrashort peptide bioconjugates are exclusively antifungal agents and synergize with cyclodextrin and amphotericin B
Year 2012
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.