Chol-KAaK

General Information


DRACP ID  DRACP02049

Peptide Name   Chol-KAaK

Sequence  KAaK

Sequence Length  4

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Human erythrocytes: 50% Hemolysis=60 µM

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antimicrobial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Cholesterol

C-terminal Modification  Amidation

Other Modification  k=D-Lys

Chiral  Mix



Physicochemical Information


Formula  C15H29N5O3

Absent amino acids  CDEFGHILMNPQRSTVWY

Common amino acids  K

Mass  38112

Pl  10.81

Basic residues  2

Acidic residues  0

Hydrophobic residues  1

Net charge  2

Boman Index  -929

Hydrophobicity  -150

Aliphatic Index  25

Half Life 
  /

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 22006001

Title  Ultrashort peptide bioconjugates are exclusively antifungal agents and synergize with cyclodextrin and amphotericin B

Doi 10.1128/AAC.00468-11

Year  2012

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.