This work is licensed under a Creative Commons Attribution 4.0 International License.
Cathelicidin-BF
General Information
DRACP ID DRACP02064
Peptide Name Cathelicidin-BF
Sequence KFFRKLKKSVKKRAKEFFKKPRVIGVSIPF
Sequence Length 30
UniProt ID B6D434
PubChem CID Not available
Origin Bungarus fasciatus
Type Native peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HepG2 | Hepatoblastoma | Blastoma | Not active up to 400 µg/ml | Not available | Not available | 1 |
| RAW 264.7 | Mouse macrophage leukemia cell | Leukemia | Not active up to 400 µg/ml | Not available | Not available | 1 |
Hemolytic Activity Human erythrocytes: Not active up to 400 µg/ml
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antimicrobial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C176H290N48O35
Absent amino acids CDHMNQTWY
Common amino acids K
Mass 415595
Pl 12.35
Basic residues 12
Acidic residues 1
Hydrophobic residues 12
Net charge 11
Boman Index -6379
Hydrophobicity -53.67
Aliphatic Index 71.33
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 18795096
Title Snake cathelicidin from Bungarus fasciatus is a potent peptide antibiotics
Doi 10.1371/journal.pone.0003217
Year 2008
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPR_1737
This work is licensed under a Creative Commons Attribution 4.0 International License.