PL-D 41

General Information


DRACP ID  DRACP02259

Peptide Name   PL-D 41

Sequence  VRLRIRVRVIRK

Sequence Length  12

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
THP-1 Childhood acute monocytic leukemia; Acute monoblastic/monocytic leukemia Leukemia IC50=40.2 µM Resazurin assay 72 h 1

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antimicrobial



Structure Information


PDB ID  Not available

Predicted Structure  DRACP02259

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C69H134N28O13

Absent amino acids  ACDEFGHMNPQSTWY

Common amino acids  R

Mass  176038

Pl  13.1

Basic residues  6

Acidic residues  0

Hydrophobic residues  6

Net charge  6

Boman Index  -5327

Hydrophobicity  -8.33

Aliphatic Index  170

Half Life 
  Mammalian: 1 hour
  Yeast: 2 min
  E.coli: 2 min

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 23478953

Title  Targeting Mycobacterium tuberculosis and other microbial pathogens using improved synthetic antibacterial peptides

Doi 10.1128/AAC.00175-13

Year  2013

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  DBAASPS_7086

DRACP is developed by Dr.Zheng's team.