This work is licensed under a Creative Commons Attribution 4.0 International License.
Hp1035
General Information
DRACP ID DRACP02275
Peptide Name Hp1035
Sequence IFSAIGGFLKSIF
Sequence Length 13
UniProt ID P0DJ03
PubChem CID Not available
Origin Heterometrus petersii
Type Native peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| Huh7.5.1 | Adult hepatocellular carcinoma | Carcinoma | Cell viability>90%: Concentration<20 μg/ml | MTT assay | 48 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antiviral
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C70H106N14O16
Absent amino acids CDEHMNPQRTVWY
Common amino acids FI
Mass 161392
Pl 9.7
Basic residues 1
Acidic residues 0
Hydrophobic residues 8
Net charge 1
Boman Index 1996
Hydrophobicity 163.08
Aliphatic Index 127.69
Half Life
Mammalian: 20 hour
Yeast: 30 min
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 4
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 20950663
Title A new natural α-helical peptide from the venom of the scorpion Heterometrus petersii kills HCV
Doi 10.1016/j.peptides.2010.10.008
Year 2011
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPR_3354
This work is licensed under a Creative Commons Attribution 4.0 International License.