This work is licensed under a Creative Commons Attribution 4.0 International License.
MAP-04-03
General Information
DRACP ID DRACP02398
Peptide Name MAP-04-03
Sequence KWLRRVWRWWR
Sequence Length 11
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP Membrane lysis
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| MCF-7 | Invasive breast carcinoma of no special type | Carcinoma | IC50=61.5 μM | MTT assay | 48 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C85H122N28O12
Absent amino acids ACDEFGHIMNPQSTY
Common amino acids RW
Mass 190662
Pl 12.98
Basic residues 5
Acidic residues 0
Hydrophobic residues 6
Net charge 5
Boman Index -4695
Hydrophobicity -159.09
Aliphatic Index 61.82
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 22000
Absorbance 280nm 2200
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 23993331
Title Anticancer activities of an antimicrobial peptide derivative of Ixosin-B amide
Doi 10.1016/j.bmcl.2013.07.063
Year 2013
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPS_4584
This work is licensed under a Creative Commons Attribution 4.0 International License.