C6

General Information


DRACP ID  DRACP02426

Peptide Name   C6

Sequence  KRKILIL

Sequence Length  7

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
U-937 Adult acute monocytic leukemi; Acute monoblastic/monocytic leukemia Leukemia LD50>64 µM; MTC>64 µM CytoTox 96 non-radiactive cytotoxicity assay  2 h 1

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  DRACP02426

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C42H82N12O8

Absent amino acids  ACDEFGHMNPQSTVWY

Common amino acids  IKL

Mass  99040

Pl  11.82

Basic residues  3

Acidic residues  0

Hydrophobic residues  4

Net charge  3

Boman Index  -634

Hydrophobicity  61.43

Aliphatic Index  222.86

Half Life 
  Mammalian: 1.3 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 25192319

Title  Rational design of artificial β-strand-forming antimicrobial peptides with biocompatible properties

Doi 10.1021/mp500271c

Year  2014

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  DBAASPS_9121

DRACP is developed by Dr.Zheng's team.