H6

General Information


DRACP ID  DRACP02434

Peptide Name   H6

Sequence  KRKKRK

Sequence Length  6

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
U-937 Adult acute monocytic leukemi; Acute monoblastic/monocytic leukemia Leukemia LD50>64 µM; MTC>64 µM CytoTox 96 non-radiactive cytotoxicity assay  2 h 1

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  DRACP02434

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C36H74N16O7

Absent amino acids  ACDEFGHILMNPQSTVWY

Common amino acids  K

Mass  93244

Pl  12.56

Basic residues  6

Acidic residues  0

Hydrophobic residues  0

Net charge  6

Boman Index  -5204

Hydrophobicity  -410

Aliphatic Index  0

Half Life 
  Mammalian: 1.3 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 25192319

Title  Rational design of artificial β-strand-forming antimicrobial peptides with biocompatible properties

Doi 10.1021/mp500271c

Year  2014

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  DBAASPS_9140

DRACP is developed by Dr.Zheng's team.