This work is licensed under a Creative Commons Attribution 4.0 International License.
Chemokinostatin-1
General Information
DRACP ID DRACP02509
Peptide Name Chemokinostatin-1
Sequence NGRKACLNPASPIVKKIIEKMLNS
Sequence Length 24
UniProt ID P09341
PubChem CID Not available
Origin Homo sapiens (CXCL1/Gro-α)
Type Native peptide
Classification
Active ACP Cancer targeted peptides Antiangiogenic
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target CXCR
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C114H202N34O32S2
Absent amino acids DFHQTWY
Common amino acids K
Mass 303562
Pl 10.8
Basic residues 5
Acidic residues 1
Hydrophobic residues 8
Net charge 4
Boman Index -3382
Hydrophobicity -25
Aliphatic Index 101.67
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 7
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 18307172
Title Novel anti-angiogenic peptides derived from ELR-containing CXC chemokines
Year 2008
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.