This work is licensed under a Creative Commons Attribution 4.0 International License.
Chemokinostatin-5
General Information
DRACP ID DRACP02511
Peptide Name Chemokinostatin-5
Sequence NGKEICLDPEAPFLKKVIQKILD
Sequence Length 23
UniProt ID P42830
PubChem CID Not available
Origin Homo sapiens (CXCL5/ENA-78)
Type Native peptide
Classification
Active ACP Cancer targeted peptides Antiangiogenic
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target CXCR
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C119H199N29O34S
Absent amino acids HMRSTWY
Common amino acids K
Mass 300474
Pl 6.45
Basic residues 4
Acidic residues 4
Hydrophobic residues 9
Net charge 0
Boman Index -2487
Hydrophobicity -17.39
Aliphatic Index 118.7
Half Life
Mammalian: 1.4 hour
Yeast: 3 min
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 18307172
Title Novel anti-angiogenic peptides derived from ELR-containing CXC chemokines
Year 2008
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.