CLB
General Information
DRACP ID DRACP02529
Peptide Name CLB
Sequence CLB
Sequence Length 3
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
---|---|---|---|---|---|---|
CAPAN-1 | Pancreatic ductal adenocarcinoma | Carcinoma | IC50=129.0 ± 35.5 µM | MTT assay | 48 h | 1 |
MCF-7 | Invasive breast carcinoma of no special type | Carcinoma | IC50=73.7 ± 4.5 µM | MTT assay | 48 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity NIH 3T3: IC50=152.5 ± 5.6 µM
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C9H16N2O2S
Absent amino acids ADEFGHIKMNPQRSTVWY
Common amino acids CL
Mass 25216
Pl 5.92
Basic residues 0
Acidic residues 0
Hydrophobic residues 1
Net charge 0
Boman Index 620
Hydrophobicity 210
Aliphatic Index 130
Half Life
/
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 24480922
Title Identification of BP16 as a non-toxic cell-penetrating peptide with highly efficient drug delivery properties
Year 2014
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available