CLB

General Information


DRACP ID  DRACP02529

Peptide Name   CLB

Sequence  CLB

Sequence Length  3

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
CAPAN-1 Pancreatic ductal adenocarcinoma Carcinoma IC50=129.0 ± 35.5 µM MTT assay 48 h 1
MCF-7 Invasive breast carcinoma of no special type Carcinoma IC50=73.7 ± 4.5 µM MTT assay 48 h 1

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  NIH 3T3: IC50=152.5 ± 5.6 µM

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C9H16N2O2S

Absent amino acids  ADEFGHIKMNPQRSTVWY

Common amino acids  CL

Mass  25216

Pl  5.92

Basic residues  0

Acidic residues  0

Hydrophobic residues  1

Net charge  0

Boman Index  620

Hydrophobicity  210

Aliphatic Index  130

Half Life 
  /

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 24480922

Title  Identification of BP16 as a non-toxic cell-penetrating peptide with highly efficient drug delivery properties

Doi 10.1039/c3ob42422g

Year  2014

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.