This work is licensed under a Creative Commons Attribution 4.0 International License.
CLB-CREKA
General Information
DRACP ID DRACP02530
Peptide Name CLB-CREKA
Sequence CLBCREKA
Sequence Length 8
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Coupling peptide
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| CAPAN-1 | Pancreatic ductal adenocarcinoma | Carcinoma | IC50>200 µM | MTT assay | 48 h | 1 |
| MCF-7 | Invasive breast carcinoma of no special type | Carcinoma | IC50>200 µM | MTT assay | 48 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity NIH 3T3: IC50>200 µM
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C32H57N11O9S2
Absent amino acids DFGHIMNPQSTVWY
Common amino acids C
Mass 92904
Pl 8.23
Basic residues 2
Acidic residues 1
Hydrophobic residues 2
Net charge 1
Boman Index -1799
Hydrophobicity -16.25
Aliphatic Index 61.25
Half Life
/
Extinction Coefficient cystines 125
Absorbance 280nm 17.86
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 24480922
Title Identification of BP16 as a non-toxic cell-penetrating peptide with highly efficient drug delivery properties
Year 2014
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.