This work is licensed under a Creative Commons Attribution 4.0 International License.
PBP-X
General Information
DRACP ID DRACP02595
Peptide Name PBP-X
Sequence XXLIXVWAXGFXXAXXLFXGIG
Sequence Length 22
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP Membrane lysis
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HeLa | Human papillomavirus-related endocervical adenocarcinoma | Carcinoma | 8% Cytotoxicity=15 µM | CellTiter-Blue assay | 24 h | 1 |
Hemolytic Activity Sheep erythrocytes: 0% Hemolysis=15 µM
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification X=Diaminopropionic acid
Chiral L
Physicochemical Information
Formula C70H84N14O5
Absent amino acids CDEHKMNPQRSTY
Common amino acids X
Mass 256629
Pl 6.11
Basic residues 0
Acidic residues 0
Hydrophobic residues 10
Net charge 0
Boman Index 3845
Hydrophobicity 126.82
Aliphatic Index 93.18
Half Life
/
Extinction Coefficient cystines 5500
Absorbance 280nm 261.9
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30637367
Title Antimicrobial activity of a porphyrin binding peptide
Doi 110(4):e24074. doi: 10.1002/pep2.24074
Year 2018
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPS_12366
This work is licensed under a Creative Commons Attribution 4.0 International License.