Retro-inverso Mastoparan

General Information


DRACP ID  DRACP02650

Peptide Name   Retro-inverso Mastoparan

Sequence  likkalaalaklni

Sequence Length  14

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP Cell-penetrating peptides Induce apoptosis



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
U-373MG Astrocytoma Carcinoma LD50=80.40 μM MTT assay 4 h 1

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antimicrobial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  D



Physicochemical Information


Formula  H-26O-13

Absent amino acids  ACDEFGHIKLMNPQRSTVWY

Common amino acids  ACDEFGHIKLMNPQRSTVWYX

Mass  -216

Pl  6.11

Basic residues  0

Acidic residues  0

Hydrophobic residues  0

Net charge  0

Boman Index  0

Hydrophobicity  0

Aliphatic Index  0

Half Life 
  /

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 22148546

Title  Enantiomer-specific bioactivities of peptidomimetic analogues of mastoparan and mitoparan: characterization of inverso mastoparan as a highly efficient cell penetrating peptide

Doi 10.1021/bc2002924

Year  2012

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  DBAASPS_12890

DRACP is developed by Dr.Zheng's team.