This work is licensed under a Creative Commons Attribution 4.0 International License.
Mitoparan, Mastoparan [A5,8K;A10Aib]
General Information
DRACP ID DRACP02651
Peptide Name Mitoparan, Mastoparan [A5,8K;A10Aib]
Sequence INLKKLAKLXKKIL
Sequence Length 14
UniProt ID P01514
PubChem CID 101852470
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP Cell-penetrating peptides Induce apoptosis
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| U-373MG | Astrocytoma | Carcinoma | LD50=9.44 μM | MTT assay | 4 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antimicrobial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification X=AIB (Aminoisobutyric acid)
Chiral L
Physicochemical Information
Formula C73H137N19O14
Absent amino acids CDEFGHMPQRSTVWY
Common amino acids K
Mass 184709
Pl 11.4
Basic residues 5
Acidic residues 0
Hydrophobic residues 7
Net charge 5
Boman Index -306
Hydrophobicity 21.43
Aliphatic Index 174.29
Half Life
/
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 22148546
Title Enantiomer-specific bioactivities of peptidomimetic analogues of mastoparan and mitoparan: characterization of inverso mastoparan as a highly efficient cell penetrating peptide
Year 2012
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPS_12795
This work is licensed under a Creative Commons Attribution 4.0 International License.