This work is licensed under a Creative Commons Attribution 4.0 International License.
Retro Mitoparan
General Information
DRACP ID DRACP02653
Peptide Name Retro Mitoparan
Sequence LIKKXLKALKKLNI
Sequence Length 14
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP Cell-penetrating peptides Induce apoptosis
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| U-373MG | Astrocytoma | Carcinoma | LD50>100 μM | MTT assay | 4 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification X=AIB (Aminoisobutyric acid)
Chiral L
Physicochemical Information
Formula C73H137N19O14
Absent amino acids CDEFGHMPQRSTVWY
Common amino acids K
Mass 184709
Pl 11.4
Basic residues 5
Acidic residues 0
Hydrophobic residues 7
Net charge 5
Boman Index -306
Hydrophobicity 21.43
Aliphatic Index 174.29
Half Life
/
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 22148546
Title Enantiomer-specific bioactivities of peptidomimetic analogues of mastoparan and mitoparan: characterization of inverso mastoparan as a highly efficient cell penetrating peptide
Year 2012
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPS_12892
This work is licensed under a Creative Commons Attribution 4.0 International License.