This work is licensed under a Creative Commons Attribution 4.0 International License.
Retro-inverso Mitoparan
General Information
DRACP ID DRACP02654
Peptide Name Retro-inverso Mitoparan
Sequence likkXlkalkklni
Sequence Length 14
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP Cell-penetrating peptides Induce apoptosis
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| U-373MG | Astrocytoma | Carcinoma | LD50=67.15 μM | MTT assay | 4 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification X=AIB (Aminoisobutyric acid)
Chiral Mix
Physicochemical Information
Formula H-26O-13
Absent amino acids ACDEFGHIKLMNPQRSTVWY
Common amino acids X
Mass 10784
Pl 6.11
Basic residues 0
Acidic residues 0
Hydrophobic residues 0
Net charge 0
Boman Index 0
Hydrophobicity 0
Aliphatic Index 0
Half Life
/
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 22148546
Title Enantiomer-specific bioactivities of peptidomimetic analogues of mastoparan and mitoparan: characterization of inverso mastoparan as a highly efficient cell penetrating peptide
Year 2012
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPS_12893
This work is licensed under a Creative Commons Attribution 4.0 International License.