This work is licensed under a Creative Commons Attribution 4.0 International License.
HCV gp (552-566), E2-43
General Information
DRACP ID DRACP02755
Peptide Name HCV gp (552-566), E2-43
Sequence FGCTWMNSTGFTKTC
Sequence Length 15
UniProt ID Q99IB8
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| Huh7.5/CD81 (HCV infection) | Adult hepatocellular carcinoma | Carcinoma | 50% Cell death>0.1 µM | MTT assay | 48 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antiviral
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C73H106N18O22S3
Absent amino acids ADEHILPQRVY
Common amino acids T
Mass 193382
Pl 8.23
Basic residues 1
Acidic residues 0
Hydrophobic residues 3
Net charge 1
Boman Index -1079
Hydrophobicity -1.33
Aliphatic Index 0
Half Life
Mammalian: 0.8 hour
Yeast: 10 min
E.coli: >10 hour
Extinction Coefficient cystines 5625
Absorbance 280nm 401.79
Polar residues 10
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 28638089
Title A screen for inhibitory peptides of hepatitis C virus identifies a novel entry inhibitor targeting E1 and E2
Doi 10.1038/s41598-017-04274-8
Year 2017
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPS_15451
This work is licensed under a Creative Commons Attribution 4.0 International License.