This work is licensed under a Creative Commons Attribution 4.0 International License.
HCV gp (692-706), E2-78
General Information
DRACP ID DRACP02756
Peptide Name HCV gp (692-706), E2-78
Sequence GLLHLHQNIVDVQYM
Sequence Length 15
UniProt ID Q99IB8
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| Huh7.5/CD81 (HCV infection) | Adult hepatocellular carcinoma | Carcinoma | 50% Cell death>0.1 µM | MTT assay | 48 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antiviral
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C80H126N22O22S
Absent amino acids ACEFKPRSTW
Common amino acids L
Mass 203000
Pl 6.5
Basic residues 2
Acidic residues 1
Hydrophobic residues 6
Net charge 1
Boman Index -485
Hydrophobicity 27.33
Aliphatic Index 142.67
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 1490
Absorbance 280nm 106.43
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 28638089
Title A screen for inhibitory peptides of hepatitis C virus identifies a novel entry inhibitor targeting E1 and E2
Doi 10.1038/s41598-017-04274-8
Year 2017
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPS_15452
This work is licensed under a Creative Commons Attribution 4.0 International License.