This work is licensed under a Creative Commons Attribution 4.0 International License.
Modifed Opero2
General Information
DRACP ID DRACP02816
Peptide Name Modifed Opero2
Sequence GLKKVIKLLRPLL
Sequence Length 13
UniProt ID A0A0L7L9V8
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP Membrane-targeted
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| A549 | Lung adenocarcinoma | Carcinoma | CC50=50 μM | MTT assay | 24 h | 1 |
Hemolytic Activity Human erythrocytes: <10% Hemolysis=50 µM
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C72H135N19O14
Absent amino acids ACDEFHMNQSTWY
Common amino acids L
Mass 170522
Pl 11.92
Basic residues 4
Acidic residues 0
Hydrophobic residues 7
Net charge 4
Boman Index 293
Hydrophobicity 73.08
Aliphatic Index 202.31
Half Life
Mammalian: 20 hour
Yeast: 30 min
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 33063186
Title Design of antimicrobial and cytolytic peptides by computational analysis of bacterial, algal, and invertebrate proteomes
Doi 10.1007/s00726-020-02900-w
Year 2020
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPS_16910
This work is licensed under a Creative Commons Attribution 4.0 International License.