This work is licensed under a Creative Commons Attribution 4.0 International License.
Modifed Opero3
General Information
DRACP ID DRACP02817
Peptide Name Modifed Opero3
Sequence ILKPKLWKLTVVARKIIK
Sequence Length 18
UniProt ID A0A0L7LPN7
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP Membrane-targeted
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| A549 | Lung adenocarcinoma | Carcinoma | CC50=200 μM | MTT assay | 24 h | 1 |
Hemolytic Activity Human erythrocytes: <10% Hemolysis=50 µM
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C105H187N27O20
Absent amino acids CDEFGHMNQSY
Common amino acids K
Mass 245123
Pl 12.05
Basic residues 6
Acidic residues 0
Hydrophobic residues 10
Net charge 6
Boman Index -350
Hydrophobicity 43.89
Aliphatic Index 167.78
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 5500
Absorbance 280nm 323.53
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 33063186
Title Design of antimicrobial and cytolytic peptides by computational analysis of bacterial, algal, and invertebrate proteomes
Doi 10.1007/s00726-020-02900-w
Year 2020
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPS_16911
This work is licensed under a Creative Commons Attribution 4.0 International License.