This work is licensed under a Creative Commons Attribution 4.0 International License.
Phakellistatin 6
General Information
DRACP ID DRACP02942
Peptide Name Phakellistatin 6
Sequence PFPWLPI
Sequence Length 7
UniProt ID Not available
PubChem CID Not available
Origin Phakellia costata
Type Native peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| P388 | Mouse lymphoma | Lymphoma | ED50=0.18 μg/mL | Not available | Not available | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond NCB: Pro1<--->Ile7
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C47H64N8O8
Absent amino acids ACDEGHKMNQRSTVY
Common amino acids P
Mass 97627
Pl 6.11
Basic residues 0
Acidic residues 0
Hydrophobic residues 4
Net charge 0
Boman Index 1515
Hydrophobicity 77.14
Aliphatic Index 111.43
Half Life
Mammalian: >20 hour
Yeast: >20 hour
E.coli: ?
Extinction Coefficient cystines 5500
Absorbance 280nm 916.67
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 28335479
Title Phakellistatins: An Underwater Unsolved Puzzle
Year 2017
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.