This work is licensed under a Creative Commons Attribution 4.0 International License.
Phakellistatin 14
General Information
DRACP ID DRACP02945
Peptide Name Phakellistatin 14
Sequence AIPFXAX
Sequence Length 7
UniProt ID Not available
PubChem CID 11308763
Origin Phakellia sp
Type Native peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| P388 | Mouse lymphoma | Lymphoma | ED50=0.0042 μg/mL | Not available | Not available | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond NCB: Ala1<--->X7
N-terminal Modification Free
C-terminal Modification Free
Other Modification X(5)=β-OMe-Asp; X(7)=Met(SO)
Chiral L
Physicochemical Information
Formula C26H35N5O4
Absent amino acids CDEGHKLMNQRSTVWY
Common amino acids AX
Mass 80880
Pl 6.11
Basic residues 0
Acidic residues 0
Hydrophobic residues 4
Net charge 0
Boman Index 1152
Hydrophobicity 132.86
Aliphatic Index 84.29
Half Life
/
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 15679318
Title Isolation and structure of phakellistatin 14 from the Western Pacific marine sponge Phakellia sp
Year 2005
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.