This work is licensed under a Creative Commons Attribution 4.0 International License.
Oncocin Onc112 [Y6W], Onc254
General Information
DRACP ID DRACP02975
Peptide Name Oncocin Onc112 [Y6W], Onc254
Sequence VDKPPWLPRPRPPRrIYNr
Sequence Length 19
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HepG2 | Hepatoblastoma | Blastoma | 34% Killing=600 µg/ml | MTT assay | 20 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity HEK293: 55% Killing=600 µg/ml
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral Mix
Physicochemical Information
Formula C99H149N29O20
Absent amino acids ACEFGHMQST
Common amino acids P
Mass 238667
Pl 11.43
Basic residues 4
Acidic residues 1
Hydrophobic residues 4
Net charge 3
Boman Index -4960
Hydrophobicity -124.74
Aliphatic Index 56.32
Half Life
/
Extinction Coefficient cystines 6990
Absorbance 280nm 388.33
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 34902208
Title Effect of Amino Acid Substitutions on 70S Ribosomal Binding, Cellular Uptake, and Antimicrobial Activity of Oncocin Onc112
Year 2022
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPS_18911
This work is licensed under a Creative Commons Attribution 4.0 International License.