This work is licensed under a Creative Commons Attribution 4.0 International License.
Oncocin Onc112 [P12W, P13R], Onc274
General Information
DRACP ID DRACP02995
Peptide Name Oncocin Onc112 [P12W, P13R], Onc274
Sequence VDKPPYLPRPRWRRrIYNr
Sequence Length 19
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HepG2 | Hepatoblastoma | Blastoma | 43% Killing=600 µg/ml | MTT assay | 20 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity HEK293: 44% Killing=600 µg/ml
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral Mix
Physicochemical Information
Formula C104H156N32O21
Absent amino acids ACEFGHMQST
Common amino acids PR
Mass 251180
Pl 11.4
Basic residues 5
Acidic residues 1
Hydrophobic residues 4
Net charge 4
Boman Index -6466
Hydrophobicity -138.42
Aliphatic Index 56.32
Half Life
/
Extinction Coefficient cystines 8480
Absorbance 280nm 471.11
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 34902208
Title Effect of Amino Acid Substitutions on 70S Ribosomal Binding, Cellular Uptake, and Antimicrobial Activity of Oncocin Onc112
Year 2022
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPS_18937
This work is licensed under a Creative Commons Attribution 4.0 International License.