This work is licensed under a Creative Commons Attribution 4.0 International License.
Amphipathic-1d, 5D-K6L9
General Information
DRACP ID DRACP03436
Peptide Name Amphipathic-1d, 5D-K6L9
Sequence LKlLKkLlkKLLkLL
Sequence Length 15
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral Mix
Physicochemical Information
Formula C60H105N13O6
Absent amino acids ACDEFGHIMNPQRSTVWY
Common amino acids L
Mass 135449
Pl 11.1
Basic residues 3
Acidic residues 0
Hydrophobic residues 7
Net charge 3
Boman Index 1779
Hydrophobicity 99.33
Aliphatic Index 182
Half Life
/
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 35759644
Title Antimicrobial Peptides against Multidrug-Resistant Pseudomonas aeruginosa Biofilm from Cystic Fibrosis Patients
Doi Not available
Year 2022
Literature 2
Pubmed ID 22969424
Title D-alanylation of lipoteichoic acids confers resistance to cationic peptides in group B streptococcus by increasing the cell wall density
Doi Not available
Year 2012
Literature 3
Pubmed ID 16707464
Title Inhibition of tumor growth and elimination of multiple metastases in human prostate and breast xenografts by systemic inoculation of a host defense-like lytic peptide
Doi Not available
Year 2006
Literature 4
Pubmed ID 12110678
Title The consequence of sequence alteration of an amphipathic alpha-helical antimicrobial peptide and its diastereomers
Doi Not available
Year 2002
Literature 5
Pubmed ID 15019200
Title Can we predict biological activity of antimicrobial peptides from their interactions with model phospholipid membranes
Doi Not available
Year 2003
Literature 6
Pubmed ID 15273131
Title In vitro activity and potency of an intravenously injected antimicrobial peptide and its DL amino acid analog in mice infected with bacteria
Doi Not available
Year 2004
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 257
This work is licensed under a Creative Commons Attribution 4.0 International License.