Buforin-2 [F10W]

General Information


DRACP ID  DRACP03437

Peptide Name   Buforin-2 [F10W]

Sequence  TRSSRAGLQWPVGRVHRLLRK

Sequence Length  21

UniProt ID  P55897 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  DRACP03437

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C108H185N41O26

Absent amino acids  CDEFIMNY

Common amino acids  R

Mass  283082

Pl  13.1

Basic residues  7

Acidic residues  0

Hydrophobic residues  7

Net charge  7

Boman Index  -7086

Hydrophobicity  -81.43

Aliphatic Index  88.1

Half Life 
  Mammalian: 5.5 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  5500

Absorbance 280nm  275

Polar residues  5

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Dimerization of cell-penetrating buforin II enhances antimicrobial properties

Doi Not available

Year  2021

Literature 2

Pubmed ID 10913273

Title  Interactions of the novel antimicrobial peptide buforin 2 with lipid bilayers: proline as a translocation promoting factor

Doi Not available

Year  2000

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  889

DRACP is developed by Dr.Zheng's team.