Defensin MGD1(21-39) peptide P

General Information


DRACP ID  DRACP03445

Peptide Name   Defensin MGD1(21-39) peptide P

Sequence  CGGYCGGWKRKRCTSYRCG

Sequence Length  19

UniProt ID  P80571 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antiviral; Antiparasitic



Structure Information


PDB ID  Not available

Predicted Structure  DRACP03445

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C88H137N31O24S4

Absent amino acids  ADEFHILMNPQV

Common amino acids  G

Mass  246273

Pl  9.49

Basic residues  5

Acidic residues  0

Hydrophobic residues  1

Net charge  5

Boman Index  -4996

Hydrophobicity  -96.32

Aliphatic Index  0

Half Life 
  Mammalian: 1.2 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  8730

Absorbance 280nm  485

Polar residues  13

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 15480442

Title  Antiprotozoan and Antiviral Activities of Non-cytotoxic Truncated and Variant Analogues of Mussel Defensin

Doi Not available

Year  2004

Literature 2

Pubmed ID 12823551

Title  Key role of the loop connecting the two beta strands of mussel defensin in its antimicrobial activity

Doi Not available

Year  2003

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  2550

DRACP is developed by Dr.Zheng's team.