This work is licensed under a Creative Commons Attribution 4.0 International License.
K6L2W3
General Information
DRACP ID DRACP03450
Peptide Name K6L2W3
Sequence KLWKKWKKWLK
Sequence Length 11
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C81H126N20O12
Absent amino acids ACDEFGHIMNPQRSTVY
Common amino acids K
Mass 175057
Pl 11.5
Basic residues 6
Acidic residues 0
Hydrophobic residues 5
Net charge 6
Boman Index -1647
Hydrophobicity -168.18
Aliphatic Index 70.91
Half Life
Mammalian:
Yeast:
E.coli:
Extinction Coefficient cystines 16500
Absorbance 280nm 1650
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30447380
Title Repurposing azithromycin and rifampicin against Gram-negative pathogens by combination with peptide potentiators
Doi Not available
Year 2019
Literature 2
Pubmed ID 28105725
Title Antifungal peptides: a potential new class of antifungals for treating vulvovaginal candidiasis caused by fluconazole-resistant Candida albicans
Doi Not available
Year 2017
Literature 3
Pubmed ID 19285481
Title Cell specificity, anti-inflammatory activity, and plausible bactericidal mechanism of designed Trp-rich model antimicrobial peptides
Doi Not available
Year 2009
Literature 4
Pubmed ID 20621141
Title Mammalian cell toxicity and candidacidal mechanism of Arg- or Lys-containing Trp-rich model antimicrobial peptides and their d-enantiomeric peptides
Doi Not available
Year 2010
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 2820
This work is licensed under a Creative Commons Attribution 4.0 International License.