This work is licensed under a Creative Commons Attribution 4.0 International License.
A47 A1 guan / Apidaecin 1b O1 R10 acid guan, Api137
General Information
DRACP ID DRACP03451
Peptide Name A47 A1 guan / Apidaecin 1b O1 R10 acid guan, Api137
Sequence XNNRPVYIPRPRPPHPRL
Sequence Length 18
UniProt ID Q06602
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification GUAN
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C94H149N33O20
Absent amino acids ACDEFGKMQSTW
Common amino acids P
Mass 247480
Pl 12.5
Basic residues 5
Acidic residues 0
Hydrophobic residues 3
Net charge 5
Boman Index -6388
Hydrophobicity -147.78
Aliphatic Index 59.44
Half Life
/
Extinction Coefficient cystines 1490
Absorbance 280nm 87.65
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 35453182
Title Antimicrobial Activity and 70S Ribosome Binding of Apidaecin-Derived Api805 with Increased Bacterial Uptake Rate
Doi Not available
Year 2022
Literature 2
Pubmed ID 27285299
Title Insect-derived short proline-rich and murine cathelicidin-related antimicrobial peptides act synergistically on Gram-negative bacteria in vitro
Doi Not available
Year 2016
Literature 3
Pubmed ID 27243004
Title N-Terminal Ile-Orn- and Trp-Orn-Motif Repeats Enhance Membrane Interaction and Increase the Antimicrobial Activity of Apidaecins against Pseudomonas aeruginosa
Doi Not available
Year 2016
Literature 4
Pubmed ID Not available
Title Antibiotic Peptides
Doi Not available
Year 2010
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 2951
This work is licensed under a Creative Commons Attribution 4.0 International License.