Temporin-SHf

General Information


DRACP ID  DRACP03452

Peptide Name   Temporin-SHf

Sequence  FFFLSRIF

Sequence Length  8

UniProt ID  D4YWD1 

PubChem CID  Not available

Origin  Synthetic

Type  Native peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antiparasitic; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  DRACP03452

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C57H77N11O10

Absent amino acids  ACDEGHKMNPQTVWY

Common amino acids  F

Mass  120133

Pl  10.55

Basic residues  1

Acidic residues  0

Hydrophobic residues  6

Net charge  1

Boman Index  344

Hydrophobicity  177.5

Aliphatic Index  97.5

Half Life 
  Mammalian:
  Yeast:
  E.coli:

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 30924306

Title  Disulfide engineering on temporin-SHf: stabilizing the bioactive conformation of an ultra-short antimicrobial peptide

Doi Not available

Year  2019

Literature 2

Pubmed ID Not available

Title  A Head-to-Head Comparison of the Antimicrobial Activities of 30 Ultra-Short Antimicrobial Peptides Against Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans

Doi Not available

Year  2015

Literature 3

Pubmed ID 26181487

Title  Structure-Activity Relationship-based Optimization of Small Temporin-SHf Analogs with Potent Antibacterial Activity

Doi Not available

Year  2015

Literature 4

Pubmed ID 20308076

Title  Temporin-SHf, a new type of phe-rich and hydrophobic ultrashort antimicrobial peptide

Doi Not available

Year  2010

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  3232

DRACP is developed by Dr.Zheng's team.