Halictine-1/6, HAL-1/6

General Information


DRACP ID  DRACP03454

Peptide Name   Halictine-1/6, HAL-1/6

Sequence  GMWSKILGHLIK

Sequence Length  12

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  DRACP03454

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C65H107N17O14S

Absent amino acids  ACDEFNPQRTVY

Common amino acids  GIKL

Mass  157913

Pl  10.81

Basic residues  3

Acidic residues  0

Hydrophobic residues  5

Net charge  3

Boman Index  708

Hydrophobicity  41.67

Aliphatic Index  130

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  5500

Absorbance 280nm  500

Polar residues  3

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 22100226

Title  Toxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells

Doi Not available

Year  2012

Literature 2

Pubmed ID 20198492

Title  Novel antimicrobial peptides from the venom of the eusocial bee Halictus sexcinctus (Hymenoptera: Halictidae) and their analogs

Doi Not available

Year  2010

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  3267

DRACP is developed by Dr.Zheng's team.