This work is licensed under a Creative Commons Attribution 4.0 International License.
LL-37(1-12)
General Information
DRACP ID DRACP03457
Peptide Name LL-37(1-12)
Sequence LLGDFFRKSKEK
Sequence Length 12
UniProt ID P49913
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C68H110N18O18
Absent amino acids ACHIMNPQTVWY
Common amino acids K
Mass 166411
Pl 10.5
Basic residues 4
Acidic residues 2
Hydrophobic residues 4
Net charge 2
Boman Index -3376
Hydrophobicity -93.33
Aliphatic Index 65
Half Life
Mammalian:
Yeast:
E.coli:
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 16637646
Title Solution structures of human LL-37 fragments and NMR-based identification of a minimal membrane-targeting antimicrobial and anticancer region
Doi Not available
Year 2006
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 3390
This work is licensed under a Creative Commons Attribution 4.0 International License.