D LL-37 (17-32)

General Information


DRACP ID  DRACP03459

Peptide Name   D LL-37 (17-32)

Sequence  FKRiVQRiKDFlRNLV

Sequence Length  16

UniProt ID  P49913 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  Mix



Physicochemical Information


Formula  C77H122N26O15

Absent amino acids  ACEGHIMPSTWY

Common amino acids  R

Mass  191970

Pl  12.24

Basic residues  5

Acidic residues  1

Hydrophobic residues  5

Net charge  4

Boman Index  -5780

Hydrophobicity  -87.5

Aliphatic Index  60.63

Half Life 
  /

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 16637646

Title  Solution structures of human LL-37 fragments and NMR-based identification of a minimal membrane-targeting antimicrobial and anticancer region

Doi Not available

Year  2006

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  3395

DRACP is developed by Dr.Zheng's team.