Temporin-HN1, Tiannanensin

General Information


DRACP ID  DRACP03463

Peptide Name   Temporin-HN1, Tiannanensin

Sequence  AILTTLANWARKFL

Sequence Length  14

UniProt ID  H8ZRU0  E7EKD0 

PubChem CID  Not available

Origin  Animalia

Type  Native peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  DRACP03463

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C77H124N20O18

Absent amino acids  CDEGHMPQSVY

Common amino acids  AL

Mass  185003

Pl  11.65

Basic residues  2

Acidic residues  0

Hydrophobic residues  9

Net charge  2

Boman Index  -183

Hydrophobicity  70.71

Aliphatic Index  132.86

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  5500

Absorbance 280nm  423.08

Polar residues  3

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 21963433

Title  Host defense peptides in skin secretions of Odorrana tiannanensis: Proof for other survival strategy of the frog than merely anti-microbial

Doi Not available

Year  2012

Literature 2

Pubmed ID 22450466

Title  Novel antimicrobial peptides isolated from the skin secretions of Hainan odorous frog, Odorrana hainanensis

Doi Not available

Year  2012

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  3561

DRACP is developed by Dr.Zheng's team.