This work is licensed under a Creative Commons Attribution 4.0 International License.
Retrocyclin-1, RC-100
General Information
DRACP ID DRACP03464
Peptide Name Retrocyclin-1, RC-100
Sequence GICRCICGRGICRCICGR
Sequence Length 18
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antiviral
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C74H136N30O19S6
Absent amino acids ADEFHKLMNPQSTVWY
Common amino acids C
Mass 224588
Pl 8.64
Basic residues 4
Acidic residues 0
Hydrophobic residues 4
Net charge 4
Boman Index -2856
Hydrophobicity 74.44
Aliphatic Index 86.67
Half Life
Mammalian: 4.4 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 375
Absorbance 280nm 22.06
Polar residues 10
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 16790431
Title Retrocyclins kill bacilli and germinating spores of Bacillus anthracis and inactivate anthrax lethal toxin
Doi Not available
Year 2006
Literature 2
Pubmed ID 15210812
Title Activity of alpha- and theta-defensins against primary isolates of HIV-1
Doi Not available
Year 2004
Literature 3
Pubmed ID 15175019
Title A theta-defensin composed exclusively of D-amino acids is active against HIV-1
Doi Not available
Year 2004
Literature 4
Pubmed ID 11854483
Title Retrocyclin: a primate peptide that protects cells from infection by T- and M-tropic strains of HIV-1
Doi Not available
Year 2002
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 3807
This work is licensed under a Creative Commons Attribution 4.0 International License.