Alyteserin-2a [A10W][N15k]
General Information
DRACP ID DRACP03467
Peptide Name Alyteserin-2a [A10W][N15k]
Sequence ILGKLLSTAWGLLSkL
Sequence Length 16
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral Mix
Physicochemical Information
Formula C76H127N17O18
Absent amino acids CDEFHMNPQRVY
Common amino acids L
Mass 183470
Pl 9.7
Basic residues 1
Acidic residues 0
Hydrophobic residues 9
Net charge 1
Boman Index 2554
Hydrophobicity 132.5
Aliphatic Index 176.88
Half Life
/
Extinction Coefficient cystines 5500
Absorbance 280nm 366.67
Polar residues 5
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 22965637
Title Transformation of the naturally occurring frog skin peptide, alyteserin-2a into a potent, non-toxic anti-cancer agent
Doi Not available
Year 2013
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 4377