Alyteserin-2a [A10W][G11k][N15k]

General Information


DRACP ID  DRACP03468

Peptide Name   Alyteserin-2a [A10W][G11k][N15k]

Sequence  ILGKLLSTAWkLLSkL

Sequence Length  16

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  Mix



Physicochemical Information


Formula  C74H122N16O16

Absent amino acids  CDEFHMNPQRVY

Common amino acids  L

Mass  175963

Pl  9.7

Basic residues  1

Acidic residues  0

Hydrophobic residues  9

Net charge  1

Boman Index  2460

Hydrophobicity  135

Aliphatic Index  176.88

Half Life 
  /

Extinction Coefficient cystines  5500

Absorbance 280nm  366.67

Polar residues  4

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 22965637

Title  Transformation of the naturally occurring frog skin peptide, alyteserin-2a into a potent, non-toxic anti-cancer agent

Doi Not available

Year  2013

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  4378

DRACP is developed by Dr.Zheng's team.