Esculentin-2CHa (1-30)

General Information


DRACP ID  DRACP03469

Peptide Name   Esculentin-2CHa (1-30)

Sequence  GFSSIFRGVAKFASKGLGKDLAKLGVDLVA

Sequence Length  30

UniProt ID  D3UA61 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  DRACP03469

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C141H231N37O38

Absent amino acids  CEHMNPQTWY

Common amino acids  G

Mass  357008

Pl  10.79

Basic residues  5

Acidic residues  2

Hydrophobic residues  15

Net charge  3

Boman Index  -716

Hydrophobicity  54.67

Aliphatic Index  107.33

Half Life 
  Mammalian: 20 hour
  Yeast: 30 min
  E.coli: >10 hour

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  8

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 23159562

Title  Esculentin-2CHa: a host-defense peptide with differential cytotoxicity against bacteria, erythrocytes and tumor cells

Doi Not available

Year  2013

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  4388

DRACP is developed by Dr.Zheng's team.