Esculentin-2CHa (11-37)
General Information
DRACP ID DRACP03470
Peptide Name Esculentin-2CHa (11-37)
Sequence KFASKGLGKDLAKLGVDLVACKISKQC
Sequence Length 27
UniProt ID D3UA61
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C125H218N34O35S2
Absent amino acids EHMNPRTWY
Common amino acids K
Mass 328541
Pl 10.14
Basic residues 6
Acidic residues 2
Hydrophobic residues 11
Net charge 4
Boman Index -1661
Hydrophobicity 17.04
Aliphatic Index 104.81
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 125
Absorbance 280nm 4.81
Polar residues 7
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 23159562
Title Esculentin-2CHa: a host-defense peptide with differential cytotoxicity against bacteria, erythrocytes and tumor cells
Doi Not available
Year 2013
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 4390